Histiocytosis

Special oncology - educational materials

Langerhans cell histiocytosis (LCH), histiocytosis X Etiology, pathogenesis, diagnosis
granulomas composed of Langerhans cells, macrophages, lymphocytes, eosinophils
LC and lymphocytes produce cytokines (IL-1, IL-2, IL-3, IL-4, IL-6, IFNγ, TNFα), provoking fever, osteolysis etc.
Langerhans cell – APC dendritic cell skin, in LCH activated
CD1a antigen, cytoplasmatic S100 protein, Birbeck granules
Reactive or tumorous disorder?
Clonal proliferative tumorous disorder with variabile clinical manifestation

Attachment   Date Size Availability [?] Clinically sensitive [?] Licence
 Histiocytosis 10.9.2013 788.09 KB faculty member Creative Commons License

Courses

Creative Commons LicenseContribution content is subject to licence Creative Commons Uveďte autora-Neužívejte dílo komerčně-Nezasahujte do díla Attribution 3.0 Czech Republic